Dithiophosphate-Induced Redox Conversions of Reduced and Oxidized Glutathione

Endoplasmic reticulum : Reduced and oxidized glutathione

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Division of Molecular and Systems Toxicology, Department of Pharmaceutical 7
 Sciences, University of Basel, 4056 Basel, Switzerland 8
 2 Swiss Center for Applied Human Toxicology, University of Basel, 4056 Basel, 9
 Switzerland 10
 3 INRES – Chemical Signalling, University of Bonn, 53113 Bonn, Germany 11
 4 Department of Biology, University of Copenhagen, 2200 Copenhagen N, Denmark 12
 5 D...

Cyclophosphamide-Induced Lipid Peroxidation and Changes in Cholesterol Content: Protective Role of Reduced Glutathione

       The study was designed with an aim to evaluate the protective effects of reduced glutathione on cyclophosphamide induced lipid peroxidation and also changes in cholesterol content. Goat liver and white New Zealand rabbit were used as lipid source for the models. Lipid peroxidation study was performed by measuring the malondial...

Effect of orally administered reduced- and oxidized-glutathione against acetaminophen-induced liver injury in rats.

To investigate the effects of orally administered reduced-glutathione (GSH) and oxidized-glutathione (GSSG) on liver GSH repletion and liver injury, acetaminophen (AAP) highly loaded rats were used. Orally administered GSH, dependent on dosage, indicated a protective effect against AAP-induced hepatotoxicity. This effect was associated with a recovery of liver GSH levels. Orally administered GS...

Glutathione-s-transferase, reduced glutathione and oxidized glutathione: An adjuvant to general anesthesia with halothane or isoflurane

Halothane and enflurane administration increased the plasma GSH-Px activity and reduced zinc levels. In addition, they lowered SOD and GSH-Px activities and trace element levels on erythrocytes. Isoflurane had no effect on plasma antioxidant enzymes, but, similar to the other, isoflurane decreased the plasma zinc levels, erythrocyte SOD and GSH-Px activities and trace element levels.

A Rapid CE Assay for the Direct Quantification of Reduced and Oxidized Glutathione in Whole Blood